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Perozo, Eduardo
One or more keywords matched the following items that are connected to Perozo, Eduardo
Item TypeName
Concept Asparagine
Concept Biotransformation
Concept Amino Acid Sequence
Concept Adenosine Triphosphate
Concept Allosteric Regulation
Concept Cell Membrane Permeability
Concept Anions
Concept Circular Dichroism
Concept Arginine
Concept Aspartic Acid
Concept Bacteriorhodopsins
Concept Chemistry
Concept Cadmium
Concept Carbon Isotopes
Concept Binding Sites
Concept Biological Transport
Concept Biophysics
Concept Ciona intestinalis
Concept Copper
Concept Crystallography
Concept Cysteine
Concept Dimethyl Sulfoxide
Concept Immunoglobulin Fab Fragments
Concept Diffusion
Concept Drosophila
Concept Edetic Acid
Concept Electrophoresis, Polyacrylamide Gel
Concept Electrophysiology
Concept Energy Transfer
Concept Immunoglobulin Fragments
Concept Drosophila melanogaster
Concept Spindle Apparatus
Concept Dialysis
Concept Electron Spin Resonance Spectroscopy
Concept Escherichia coli
Concept Maleimides
Concept Leukocytes
Concept Moths
Concept Mammals
Concept Nitrates
Concept Hot Temperature
Concept Ion Channels
Concept Isoleucine
Concept Neutrophils
Concept Oxygen Isotopes
Concept Phenylalanine
Concept Phosphorylation
Concept Magnetic Resonance Spectroscopy
Concept Oxygen
Concept Protein Binding
Concept Protein Conformation
Concept Xenopus
Concept Potassium Channels
Concept Tetrodotoxin
Concept Humans
Concept Receptors, N-Methyl-D-Aspartate
Concept Spectrophotometry, Infrared
Concept Tryptophan
Concept Ion Transport
Concept Sequence Homology, Amino Acid
Concept Spectroscopy, Fourier Transform Infrared
Concept Xenopus laevis
Concept Drug Design
Concept Sodium Channels
Concept Cryoelectron Microscopy
Concept Protein Renaturation
Concept Water
Concept Protein Structure, Quaternary
Concept Up-Regulation
Concept Ion Channel Gating
Concept Molecular Conformation
Concept Respiratory Burst
Concept Protein Structure, Tertiary
Concept Methionine
Concept Microtubules
Concept Proton Pumps
Concept Crystallography, X-Ray
Concept Kv1.3 Potassium Channel
Concept Acrosome Reaction
Concept Potassium Channel Blockers
Concept Protein Structure, Secondary
Concept Gap Junctions
Concept Periplasmic Binding Proteins
Concept Decapodiformes
Concept Shaker Superfamily of Potassium Channels
Concept Ether-A-Go-Go Potassium Channels
Concept Nuclear Magnetic Resonance, Biomolecular
Concept Amino Acid Motifs
Concept Potassium Channels, Inwardly Rectifying
Concept Arabidopsis Proteins
Concept Databases, Protein
Concept Mechanotransduction, Cellular
Concept Spectrometry, Fluorescence
Concept Structure-Activity Relationship
Concept HEK293 Cells
Concept Rats
Concept Spectrophotometry, Ultraviolet
Concept Staphylococcus aureus
Concept Protein Multimerization
Concept Open Reading Frames
Concept Molecular Structure
Concept ATP-Binding Cassette Transporters
Concept HIV Protease Inhibitors
Concept Arabidopsis
Concept Halorhodopsins
Concept Anion Transport Proteins
Concept Peptide Library
Concept Cation Transport Proteins
Concept Structural Homology, Protein
Concept Kv1.2 Potassium Channel
Concept Protein Stability
Concept Antibodies
Concept Axons
Concept Crystallization
Concept Electrochemistry
Concept Histidine
Concept Kinetics
Concept Membrane Potentials
Concept T-Lymphocytes
Concept Signal Transduction
Concept Computational Biology
Concept Quantitative Structure-Activity Relationship
Concept Potassium Channels, Voltage-Gated
Concept Potassium Channels, Calcium-Activated
Concept Membrane Transport Proteins
Concept Large-Conductance Calcium-Activated Potassium Channels
Concept Biophysical Phenomena
Concept Molecular Dynamics Simulation
Academic Article Voltage activation of reconstituted sodium channels: use of bacteriorhodopsin as a light-driven current source.
Academic Article Structural dynamics of the Streptomyces lividans K+ channel (SKC1): secondary structure characterization from FTIR spectroscopy.
Academic Article Three-dimensional architecture and gating mechanism of a K+ channel studied by EPR spectroscopy.
Academic Article Structural dynamics of the Streptomyces lividans K+ channel (SKC1): oligomeric stoichiometry and stability.
Academic Article Shedding light on voltage-dependent gating.
Academic Article pH-dependent gating in the Streptomyces lividans K+ channel.
Academic Article Gating currents in Shaker K+ channels. Implications for activation and inactivation models.
Academic Article Molecular architecture of full-length KcsA: role of cytoplasmic domains in ion permeation and activation gating.
Academic Article Structure of the KcsA channel intracellular gate in the open state.
Academic Article Structure and packing orientation of transmembrane segments in voltage-dependent channels. Lessons from perturbation analysis.
Academic Article Structural rearrangements underlying K+-channel activation gating.
Academic Article Site-directed spin-labeling analysis of reconstituted Mscl in the closed state.
Academic Article EPR approaches to ion channel structure and function.
Academic Article Physical principles underlying the transduction of bilayer deformation forces during mechanosensitive channel gating.
Academic Article Open channel structure of MscL and the gating mechanism of mechanosensitive channels.
Academic Article New structural perspectives on K(+) channel gating.
Academic Article Structural biology. Force and voltage sensors in one structure.
Academic Article Structure and mechanism in prokaryotic mechanosensitive channels.
Academic Article Single channel studies of the phosphorylation of K+ channels in the squid giant axon. I. Steady-state conditions.
Academic Article Calculation of rigid-body conformational changes using restraint-driven Cartesian transformations.
Academic Article Molecular basis of gating charge immobilization in Shaker potassium channels.
Academic Article Electrostatic interaction of a K+ channel RCK domain with charged membrane surfaces.
Academic Article Gating prokaryotic mechanosensitive channels.
Academic Article Voltage-dependent gating at the KcsA selectivity filter.
Academic Article An optimized purification and reconstitution method for the MscS channel: strategies for spectroscopical analysis.
Academic Article Phosphorylation affects voltage gating of the delayed rectifier K+ channel by electrostatic interactions.
Academic Article Phosphorylation of K+ channels in the squid giant axon. A mechanistic analysis.
Academic Article How to gate an ion channel: lessons from MthK.
Academic Article Asymmetry in the structure of the ABC transporter-binding protein complex BtuCD-BtuF.
Academic Article Single channel studies of the phosphorylation of K+ channels in the squid giant axon. II. Nonstationary conditions.
Academic Article Distinct gate conformations of the ABC transporter BtuCD revealed by electron spin resonance spectroscopy and chemical cross-linking.
Academic Article Structural biology: A channel with a twist.
Academic Article A molecular mechanism for proton-dependent gating in KcsA.
Academic Article Molecular determinants of gating at the potassium-channel selectivity filter.
Academic Article Design and characterization of a constitutively open KcsA.
Academic Article Structural basis for the coupling between activation and inactivation gates in K(+) channels.
Academic Article Ion conduction through MscS as determined by electrophysiology and simulation.
Academic Article On the structural basis of modal gating behavior in K(+) channels.
Academic Article Up a hydrophobic creek with a short paddle.
Academic Article Dynamics of "flap" structures in three HIV-1 protease/inhibitor complexes probed by total chemical synthesis and pulse-EPR spectroscopy.
Academic Article A quantitative description of KcsA gating I: macroscopic currents.
Academic Article A quantitative description of KcsA gating II: single-channel currents.
Academic Article Mechanism of activation gating in the full-length KcsA K+ channel.
Academic Article Molecular coupling in the human ether-a-go-go-related gene-1 (hERG1) K+ channel inactivation pathway.
Academic Article A designer ligand specific for Kv1.3 channels from a scorpion neurotoxin-based library.
Academic Article Structural refinement of membrane proteins by restrained molecular dynamics and solvent accessibility data.
Academic Article A structural mechanism for MscS gating in lipid bilayers.
Academic Article Crystal structure of full-length KcsA in its closed conformation.
Academic Article The activated state of a sodium channel voltage sensor in a membrane environment.
Academic Article An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations.
Academic Article Spin-labeled amphotericin B: synthesis, characterization, biological and spectroscopic properties.
Academic Article Removal of transducer HtrI allows electrogenic proton translocation by sensory rhodopsin I.
Academic Article A multipoint hydrogen-bond network underlying KcsA C-type inactivation.
Academic Article Modulation of K channels in dialyzed squid axons. ATP-mediated phosphorylation.
Academic Article Thermodynamic coupling between activation and inactivation gating in potassium channels revealed by free energy molecular dynamics simulations.
Academic Article Mechanism of Cd2+ coordination during slow inactivation in potassium channels.
Academic Article Symmetry-constrained analysis of pulsed double electron-electron resonance (DEER) spectroscopy reveals the dynamic nature of the KcsA activation gate.
Academic Article Gating of Shaker K+ channels: I. Ionic and gating currents.
Academic Article S4 mutations alter gating currents of Shaker K channels.
Academic Article Purification and reconstitution of functional Shaker K+ channels assayed with a light-driven voltage-control system.
Academic Article Three-dimensional architecture of membrane-embedded MscS in the closed conformation.
Academic Article Gating of Shaker K+ channels: II. The components of gating currents and a model of channel activation.
Academic Article Reactions of cysteines substituted in the amphipathic N-terminal tail of a bacterial potassium channel with hydrophilic and hydrophobic maleimides.
Academic Article The voltage sensor and the gate in ion channels.
Academic Article Molecular architecture of the KvAP voltage-dependent K+ channel in a lipid bilayer.
Academic Article Explicit treatment of spin labels in modeling of distance constraints from dipolar EPR and DEER.
Academic Article Detection of the opening of the bundle crossing in KcsA with fluorescence lifetime spectroscopy reveals the existence of two gates for ion conduction.
Academic Article Molecular driving forces determining potassium channel slow inactivation.
Academic Article Structural dynamics of an isolated voltage-sensor domain in a lipid bilayer.
Academic Article Structural mechanism of C-type inactivation in K(+) channels.
Academic Article Structural dynamics of the magnesium-bound conformation of CorA in a lipid bilayer.
Academic Article Protein conformational dynamics in the mechanism of HIV-1 protease catalysis.
Academic Article Chemical modification of squid axon K+ channel -SH groups with the organic mercurial compound p-hydroxymercuriphenylsulfonic acid (PHMPS).
Academic Article Gating currents from a nonconducting mutant reveal open-closed conformations in Shaker K+ channels.
Academic Article Binding of the CYK-4 subunit of the centralspindlin complex induces a large scale conformational change in the kinesin subunit.
Academic Article Expression, purification, and reconstitution of the voltage-sensing domain from Ci-VSP.
Academic Article Recovery from slow inactivation in K+ channels is controlled by water molecules.
Academic Article Importance of lipid-pore loop interface for potassium channel structure and function.
Academic Article Structural basis of lipid-driven conformational transitions in the KvAP voltage-sensing domain.
Academic Article A repulsion mechanism explains magnesium permeation and selectivity in CorA.
Academic Article Dynamics transitions at the outer vestibule of the KcsA potassium channel during gating.
Academic Article Biochemical and structural analysis of the hyperpolarization-activated K(+) channel MVP.
Academic Article Conformational dynamics at the inner gate of KcsA during activation.
Academic Article Biomolecular DNP-Supported NMR Spectroscopy using Site-Directed Spin Labeling.
Academic Article Resting state of the human proton channel dimer in a lipid bilayer.
Academic Article Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating.
Academic Article Multi-ion free energy landscapes underscore the microscopic mechanism of ion selectivity in the KcsA channel.
Academic Article The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channels.
Academic Article Instantaneous ion configurations in the K+ ion channel selectivity filter revealed by 2D IR spectroscopy.
Academic Article From Nanodiscs to Isotropic Bicelles: A Procedure for Solution Nuclear Magnetic Resonance Studies of Detergent-Sensitive Integral Membrane Proteins.
Academic Article Toward a structural blueprint for bilayer-mediated channel mechanosensitivity.
Academic Article Probing the Effects of Gating on the Ion Occupancy of the K+ Channel Selectivity Filter Using Two-Dimensional Infrared Spectroscopy.
Academic Article Chemical substitutions in the selectivity filter of potassium channels do not rule out constricted-like conformations for C-type inactivation.
Academic Article The gating cycle of a K+ channel at atomic resolution.
Academic Article Towards a Structural View of Drug Binding to hERG K+ Channels.
Academic Article Role of human Hv1 channels in sperm capacitation and white blood cell respiratory burst established by a designed peptide inhibitor.
Academic Article Never at rest: insights into the conformational dynamics of ion channels from cryo-electron microscopy.
Academic Article Rapid constriction of the selectivity filter underlies C-type inactivation in the KcsA potassium channel.
Academic Article Structural Dynamics of the MscL C-terminal Domain.
Academic Article De novo GRIN variants in NMDA receptor M2 channel pore-forming loop are associated with neurological diseases.
Academic Article Real time dynamics of Gating-Related conformational changes in CorA.
Academic Article Molecular basis of force-from-lipids gating in the mechanosensitive channel MscS.
Academic Article Electromechanical coupling in the hyperpolarization-activated K+ channel KAT1.
Academic Article Mechanism of C-type inactivation in the hERG potassium channel.
Academic Article Direct activation of the proton channel by albumin leads to human sperm capacitation and sustained release of inflammatory mediators by neutrophils.
Academic Article Computational study of non-conductive selectivity filter conformations and C-type inactivation in a voltage-dependent potassium channel.
Academic Article The conformational cycle of prestin underlies outer-hair cell electromotility.
Academic Article Molecular determinants of inhibition of the human proton channel hHv1 by the designer peptide C6 and a bivalent derivative.
Academic Article Mechanism of voltage sensing in Ca2+- and voltage-activated K+ (BK) channels.
Academic Article Mechanism of voltage gating in the voltage-sensing phosphatase Ci-VSP.
Academic Article State-specific morphological deformations of the lipid bilayer explain mechanosensitive gating of MscS ion channels.
Concept ERG1 Potassium Channel
Concept Protein Domains
Concept Voltage-Gated Sodium Channels
Grant Membrane Protein Structural Dynamics Consortium
Grant MOLECULAR ARCHITECTURE OF POTASSIUM CHANNELS
Academic Article Conformation-specific Synthetic Antibodies Discriminate Multiple Functional States of the Ion Channel CorA.
Academic Article Anionic omega currents from single countercharge mutants in the voltage-sensing domain of Ci-VSP.
Academic Article Folding of prestin's anion-binding site and the mechanism of outer hair cell electromotility.
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  • Kv1
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  • Potassium Channel